Valproate chez les hommes : trois mois de contraception sont recommandés

46

Une étude suggère un risque accru de troubles neurologiques et du développement chez des enfants dont le père a été traité par valproate dans les trois mois avant la conception, en comparaison à un traitement par lamotrigine ou lévétiracétam.

Selon la situation du patient, une contraception peut être mise en place pendant le traitement ; elle doit être maintenue au moins trois mois après l’arrêt de celui-ci. En complément de l’alerte émise en août 2023 sur le risque potentiel de troubles neurologiques et du développement chez les enfants dont les pères ont été traités par valproate ou ses dérivés dans les 3 mois précédant la conception, l’Agence nationale de sécurité du médicament et des pro- duits de santé (ANSM) précise la durée de contraception à recommander :
– après discussion avec le médecin, mise en place de mesures contraceptives efficaces pendant le traitement et au moins 3 mois après l’arrêt de celui-ci,
– pas de don de sperme pendant le traitement et au moins 3 mois après l’arrêt de celui-ci. Il est recommandé aux hommes qui désirent avoir un enfant de parler de ce projet avec leur médecin afin d’évoquer le risque potentiel et les alternatives envisageables, sans perte de chance sur l’évolution de la maladie.

Le traitement par valproate ou un de ses dérivés ne doit pas être arrêté sans avis du médecin. Rappelons que le valproate (et dérivés) est un agent tératogène connu en cas d’exposition du fœtus au cours de la grossesse. Il augmente le risque de malformations congénitales (11 %) et de troubles neurodéveloppementaux collaboration précieuse que nous jetons les bases d’un avenir où le vieillissement sera synonyme de vitalité, de bien-être et de qualité de vie.

46 thoughts on “Valproate chez les hommes : trois mois de contraception sont recommandés

  1. Hi there, I found your blog by means of Google while searching for a similar matter, your site got here up, it seems great.
    I have bookmarked it in my google bookmarks.
    Hi there, just become aware of your blog via Google, and located that it’s truly informative.
    I’m gonna watch out for brussels. I will appreciate if you
    proceed this in future. Lots of other folks can be benefited out of your writing.
    Cheers!

  2. Good post! We are linking to this particularly great article on our website. Keep up the great writing.

  3. Oh my goodness! Impressive article dude! Thanks, However I am experiencing difficulties with your RSS. I don’t know why I cannot join it. Is there anyone else getting identical RSS issues? Anyone that knows the answer will you kindly respond? Thanx!!

  4. Having read this I believed it was extremely enlightening. I appreciate you finding the time and energy to put this article together. I once again find myself spending way too much time both reading and leaving comments. But so what, it was still worth it!

  5. That is a great tip particularly to those fresh to the blogosphere. Short but very accurate info… Thank you for sharing this one. A must read article!

  6. Aw, this was an extremely nice post. Taking the time and actual effort to generate a superb article… but what can I say… I hesitate a whole lot and don’t manage to get nearly anything done.

  7. I would like to thank you for the efforts you have put in writing this website. I am hoping to check out the same high-grade content by you later on as well. In fact, your creative writing abilities has motivated me to get my own, personal blog now 😉

  8. Way cool! Some very valid points! I appreciate you writing this article plus the rest of the website is also very good.

  9. A fascinating discussion is worth comment. There’s no doubt that that you should write more on this subject, it may not be a taboo matter but usually folks don’t speak about such issues. To the next! All the best!

  10. Spot on with this write-up, I really believe that this amazing site needs much more attention. I’ll probably be back again to read through more, thanks for the advice!

  11. I’m very pleased to uncover this great site. I wanted to thank you for ones time for this particularly fantastic read!! I definitely savored every little bit of it and I have you book-marked to check out new stuff on your web site.

  12. Everything is very open with a very clear explanation of the challenges. It was definitely informative. Your site is extremely helpful. Thanks for sharing!

  13. It’s difficult to find knowledgeable people about this topic, but you seem like you know what you’re talking about! Thanks

  14. Your style is so unique compared to other people I have read stuff from. Thanks for posting when you have the opportunity, Guess I will just book mark this blog.

  15. This is the right web site for everyone who hopes to understand this topic. You realize so much its almost hard to argue with you (not that I personally would want to…HaHa). You certainly put a fresh spin on a subject which has been written about for decades. Great stuff, just excellent.

  16. You made some really good points there. I looked on the internet to find out more about the issue and found most people will go along with your views on this web site.

  17. Your style is unique compared to other people I’ve read stuff from. Thanks for posting when you have the opportunity, Guess I will just bookmark this blog.

  18. As somebody that’s constantly been cautious about my blood sugar level, discovering Sugar Defender has been an alleviation. I
    really feel so much extra in control, and my recent
    check-ups have shown favorable renovations. Knowing I have a trusted supplement to sustain my regular offers me peace of mind.
    I’m so thankful for Sugar Defender’s influence on my wellness!

  19. Discovering Sugar Defender has been a game-changer for me, as I have actually always been vigilant concerning managing my blood sugar level levels.
    I now really feel equipped and certain in my capability to keep healthy and balanced degrees, and my latest health
    checks have reflected this development. Having a credible supplement to enhance my a big resource of convenience, and I’m absolutely
    grateful for the significant distinction Sugar Protector has made
    in my total well-being.

  20. For years, I’ve battled unpredictable blood sugar level swings that left
    me really feeling drained and inactive. However because incorporating Sugar Defender right into my routine, I’ve
    discovered a substantial enhancement in my overall energy and stability.

    The dreadful mid-day thing of the past, and I value that this natural
    remedy accomplishes these results without any undesirable or adverse
    responses. truthfully been a transformative exploration for me.

  21. Oh my goodness! Incredible article dude! Many thanks, However I am going through problems with your RSS. I don’t know why I am unable to join it. Is there anyone else having the same RSS issues? Anyone who knows the answer can you kindly respond? Thanx!

  22. I really love your site.. Great colors & theme. Did you make this web site yourself? Please reply back as I’m looking to create my own website and would love to find out where you got this from or exactly what the theme is called. Many thanks.

  23. Introducing to you the most prestigious online entertainment address today. Visit now to experience now!

  24. Great info. Lucky me I discovered your site by chance (stumbleupon). I have book marked it for later.

Laisser un commentaire

Votre adresse e-mail ne sera pas publiée. Les champs obligatoires sont indiqués avec *